Potential Roles of YAP/TAZ Mechanotransduction in Spaceflight-Induced Liver Dysfunction

Potential Roles of YAP/TAZ Mechanotransduction in Spaceflight-Induced Liver Dysfunction

Microgravity exposure during spaceflight causes the disordered regulation of liver function, presenting a specialized mechano-biological coupling process. While YAP/TAZ serves as a typical mechanosensitive pathway involved in hepatocyte metabolism, it remains unclear whether and how it is correlated...

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Bibliographic Details
Main Authors: Wang Li, Xinyu Shu, Xiaoyu Zhang, Ziliang Zhang, Shujin Sun, Ning Li, Mian Long
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
microgravity
liver metabolism
mechanosensing
cytoskeleton
nuclear deformation
phase separation
Online Access:https://www.mdpi.com/1422-0067/24/3/2197

Internet

https://www.mdpi.com/1422-0067/24/3/2197

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