Phosphorylated ATF1 at Thr184 promotes metastasis and regulates MMP2 expression in gastric cancer

Phosphorylated ATF1 at Thr184 promotes metastasis and regulates MMP2 expression in gastric cancer

Abstract Background Studies have revealed an important role of activating transcription factor 1 (ATF1) and phosphorylated ATF1 at Ser63 in tumors. Our previous study identified Thr184 as a novel phosphorylation site of ATF1. However, the role of phosphorylated ATF1 at Thr184 (p-ATF1-T184) in tumor...

Full description

Bibliographic Details
Main Authors: Tong Li, Huiyuan Cao, Sa Wu, Peimin Zhong, Jie Ding, Jing Wang, Fangfang Wang, Zhiwei He, Guo-Liang Huang
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Journal of Translational Medicine
Subjects:
Gastric cancer
ATF1
Phosphorylation
MMP2
Online Access:https://doi.org/10.1186/s12967-022-03361-3

Internet

https://doi.org/10.1186/s12967-022-03361-3

Similar Items