Growth hormone improves growth retardation induced by rapamycin without blocking its antiproliferative and antiangiogenic effects on rat growth plate.

Growth hormone improves growth retardation induced by rapamycin without blocking its antiproliferative and antiangiogenic effects on rat growth plate.

Rapamycin, an immunosuppressant agent used in renal transplantation with antitumoral properties, has been reported to impair longitudinal growth in young individuals. As growth hormone (GH) can be used to treat growth retardation in transplanted children, we aimed this study to find out the effect o...

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Bibliographic Details
Main Authors: Óscar Álvarez-García, Enrique García-López, Vanessa Loredo, Helena Gil-Peña, Natalia Mejía-Gaviria, Julián Rodríguez-Suárez, Flor Á Ordóñez, Fernando Santos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3321024?pdf=render

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http://europepmc.org/articles/PMC3321024?pdf=render

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