Synthesis and Biological Activity of New Derivatives of Isoindoline-1,3-dione as Non-Steroidal Analgesics

Synthesis and Biological Activity of New Derivatives of Isoindoline-1,3-dione as Non-Steroidal Analgesics

A simple method for the synthesis of new derivatives of isoindoline-1,3-dione is developed in this study, which consists of the interaction of <i>N</i>-arylbenzenecarboximidamides with phthalic anhydride in benzene at reflux. It was found that carrying out the reaction without heating le...

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Bibliographic Details
Main Authors: Yulia A. Trukhanova, Denis A. Kolesnik, Elena V. Kuvaeva, Galina V. Ksenofontova, Marina V. Sopova, Igor P. Yakovlev
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Chemistry Proceedings
Subjects:
isoindoline-1,3-diones
2-(phenyl(phenylimino)methyl)isoindoline-1,3-dione
analgesic activity
<i>N</i>-substituted derivatives of phthalimide
non-steroidal analgesic
Online Access:https://www.mdpi.com/2673-4583/8/1/99

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https://www.mdpi.com/2673-4583/8/1/99

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