A remarkable age-related increase in SIRT1 protein expression against oxidative stress in elderly: SIRT1 gene variants and longevity in human.

Aging is defined as the accumulation of progressive organ dysfunction. Controlling the rate of aging by clarifying the complex pathways has a significant clinical importance. Nowadays, sirtuins have become famous molecules for slowing aging and decreasing age-related disorders. In the present study,...

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Bibliographic Details
Main Authors: Ulkan Kilic, Ozlem Gok, Ufuk Erenberk, Mehmet Rusen Dundaroz, Emel Torun, Yasar Kucukardali, Birsen Elibol-Can, Omer Uysal, Tolga Dundar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4365019?pdf=render