FOXM1D potentiates PKM2‐mediated tumor glycolysis and angiogenesis

FOXM1D potentiates PKM2‐mediated tumor glycolysis and angiogenesis

Tumor growth, especially in the late stage, requires adequate nutrients and rich vasculature, in which PKM2 plays a convergent role. It has been reported that PKM2, together with FOXM1D, is upregulated in late‐stage colorectal cancer and associated with metastasis; however, their underlying mechanis...

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Bibliographic Details
Main Authors: Wei Zhang, Xin Zhang, Sheng Huang, Jianfeng Chen, Peipei Ding, Qi Wang, Luying Li, Xinyue Lv, Ling Li, Pingzhao Zhang, Danlei Zhou, Wenyu Wen, Yiping Wang, Qun‐Ying Lei, Jiong Wu, Weiguo Hu
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Molecular Oncology
Subjects:
angiogenesis
exosome
FOXM1D
glycolysis
NF‐κB
PKM2
Online Access:https://doi.org/10.1002/1878-0261.12879

Internet

https://doi.org/10.1002/1878-0261.12879

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