The GPCR adaptor protein Norbin regulates S1PR1 trafficking and the morphology, cell cycle and survival of PC12 cells

The GPCR adaptor protein Norbin regulates S1PR1 trafficking and the morphology, cell cycle and survival of PC12 cells

Abstract Norbin is an adaptor protein that binds numerous G protein-coupled receptors (GPCRs), is highly expressed in neurons, and is essential for a functioning nervous system in rodent models. Yet, beyond its control of neurite outgrowth and synaptic plasticity, few cellular roles of Norbin have b...

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Bibliographic Details
Main Authors: Valdemar B. I. Johansen, Elizabeth Hampson, Elpida Tsonou, Chiara Pantarelli, Julia Y. Chu, Laraine Crossland, Hanneke Okkenhaug, Andrew J. Massey, David C. Hornigold, Heidi C. E. Welch, Stephen A. Chetwynd
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-45148-6

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https://doi.org/10.1038/s41598-023-45148-6

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