Stromal Cell-Derived CCL20 Promotes Tumor Progression and Osteolysis in Giant Cell Tumor of Bone

Stromal Cell-Derived CCL20 Promotes Tumor Progression and Osteolysis in Giant Cell Tumor of Bone

Background/Aims: Giant cell tumor of bone (GCTB), one of the most common primary bone tumors, leads to extensive bone destruction. However, the mechanisms underlying GCTB progression remain elusive and prognostic factors and treatment targets are required. In the current study, we explored the funct...

Full description

Bibliographic Details
Main Authors: Chenglong Zhao, Dongsheng Wang, Liang Tang, Zhichao Zhang, Song Li, Ming Qian, Zhipeng Wu, Wang Zhou, Mingyao Liu, Jian Luo, Tielong Liu, Zhenxi Li, Jianru Xiao
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
CCL20
Giant cell tumor of bone
Cell viability
Cell migration
Osteoclastogenesis
Online Access:https://www.karger.com/Article/FullText/495903

Internet

https://www.karger.com/Article/FullText/495903

Similar Items