Dynamic gut microbiome-metabolome in cationic bovine serum albumin induced experimental immune-complex glomerulonephritis and effect of losartan and mycophenolate mofetil on microbiota modulation

Dynamic gut microbiome-metabolome in cationic bovine serum albumin induced experimental immune-complex glomerulonephritis and effect of losartan and mycophenolate mofetil on microbiota modulation

Dynamic changes in gut dysbiosis and metabolomic dysregulation are associated with immune-complex glomerulonephritis (ICGN). However, an in-depth study on this topic is currently lacking. Herein, we report an ICGN model to address this gap. ICGN was induced via the intravenous injection of cationize...

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Bibliographic Details
Main Authors: Wenying Shi, Zhaojun Li, Weida Wang, Xikun Liu, Haijie Wu, Xiaoguang Chen, Xunrong Zhou, Sen Zhang
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Immune-complex glomerulonephritis
Gut microbiome
Metabolomics
Fecal microbiota transplant
Tryptophan metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177923003040

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http://www.sciencedirect.com/science/article/pii/S2095177923003040

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