Replication-dependent size reduction precedes differentiation in Chlamydia trachomatis

The vegetative forms of chlamydiae (RBs) replicate within infected cells and then convert into infectious forms (EBs). Here, the authors use quantitative 3D electron microscopy and computer modeling to show that RB size decreases with replication, and conversion into EBs correlates with an RB size t...

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Bibliographic Details
Main Authors: Jennifer K. Lee, Germán A. Enciso, Daniela Boassa, Christopher N. Chander, Tracy H. Lou, Sean S. Pairawan, Melody C. Guo, Frederic Y. M. Wan, Mark H. Ellisman, Christine Sütterlin, Ming Tan
Format: Article
Language:English
Published: Nature Portfolio 2018-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02432-0