Protein Malnutrition Modifies Innate Immunity and Gene Expression by Intestinal Epithelial Cells and Human Rotavirus Infection in Neonatal Gnotobiotic Pigs

Protein Malnutrition Modifies Innate Immunity and Gene Expression by Intestinal Epithelial Cells and Human Rotavirus Infection in Neonatal Gnotobiotic Pigs

ABSTRACT Malnutrition affects millions of children in developing countries, compromising immunity and contributing to increased rates of death from infectious diseases. Rotavirus is a major etiological agent of childhood diarrhea in developing countries, where malnutrition is prevalent. However, the...

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Bibliographic Details
Main Authors: Anastasia N. Vlasova, Francine C. Paim, Sukumar Kandasamy, Moyasar A. Alhamo, David D. Fischer, Stephanie N. Langel, Loic Deblais, Anand Kumar, Juliet Chepngeno, Lulu Shao, Huang-Chi Huang, Rosario A. Candelero-Rueda, Gireesh Rajashekara, Linda J. Saif
Format: Article
Language:English
Published: American Society for Microbiology 2017-04-01
Series:mSphere
Subjects:
intestinal epithelial cells
gnotobiotic piglets
human infant fecal microbiota
human rotavirus
innate immunity
intestinal epithelial barrier
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00046-17

Internet

https://journals.asm.org/doi/10.1128/mSphere.00046-17

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