Porphyromonas gingivalis promote microglia M1 polarization through the NF-кB signaling pathway

Background: Porphyromonas gingivalis (P.gingivalis) is associated with the onset of Alzheimer's disease (AD), but the underlying molecular mechanism is unclear. Neuroinflammation in the brain from the microglial immune response induces the pathological progression of AD. In this study, the role...

Full description

Bibliographic Details
Main Authors: Xue Li, Chao Yao, Dongmei Lan, Yurong Chen, Yan Wang, Shengcai Qi
Format: Article
Language:English
Published: Elsevier 2024-08-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024113710