Transport of Extracellular Vesicles across the Blood-Brain Barrier: Brain Pharmacokinetics and Effects of Inflammation

Transport of Extracellular Vesicles across the Blood-Brain Barrier: Brain Pharmacokinetics and Effects of Inflammation

Extracellular vesicles can cross the blood–brain barrier (BBB), but little is known about passage. Here, we used multiple-time regression analysis to examine the ability of 10 exosome populations derived from mouse, human, cancerous, and non-cancerous cell lines to cross the BBB. All crossed the BBB...

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Bibliographic Details
Main Authors: William A. Banks, Priyanka Sharma, Kristin M. Bullock, Kim M. Hansen, Nils Ludwig, Theresa L. Whiteside
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
extracellular vesicles
exosome
blood–brain barrier
pharmacokinetics
neuroinflammation
diapedesis
Online Access:https://www.mdpi.com/1422-0067/21/12/4407

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https://www.mdpi.com/1422-0067/21/12/4407

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