Deletion of IFT20 exclusively in the RPE ablates primary cilia and leads to retinal degeneration.

Deletion of IFT20 exclusively in the RPE ablates primary cilia and leads to retinal degeneration.

Vision impairment places a serious burden on the aging society, affecting the lives of millions of people. Many retinal diseases are of genetic origin, of which over 50% are due to mutations in cilia-associated genes. Most research on retinal degeneration has focused on the ciliated photoreceptor ce...

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Bibliographic Details
Main Authors: Viola Kretschmer, Sandra Schneider, Peter Andreas Matthiessen, Dominik Reichert, Nathan Hotaling, Gunnar Glasßer, Ingo Lieberwirth, Kapil Bharti, Rossella De Cegli, Ivan Conte, Emeline F Nandrot, Helen Louise May-Simera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-12-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002402&type=printable

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https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002402&type=printable

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