Patients infected with CRF07_BC have significantly lower viral loads than patients with HIV-1 subtype B: mechanism and impact on disease progression.

The circulating recombinant form (CRF) 07_BC is the most prevalent HIV-1 strain among injection drug users (IDUs) in Taiwan. It contains a 7 amino-acid deletion in its p6gag. We conducted a cohort study to compare viral loads and CD4 cell count changes between patients infected with subtype B and CR...

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Main Authors: Szu-Wei Huang, Sheng-Fan Wang, Yu-Ting Lin, Chia-Hung Yen, Chih-Hao Lee, Wing-Wai Wong, Hung-Chin Tsai, Chia-Jui Yang, Bor-Shen Hu, Yu-Huei Lin, Chin-Tien Wang, Jaang-Jiun Wang, Zixin Hu, Daniel R Kuritzkes, Yen-Hsu Chen, Yi-Ming Arthur Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0114441