Differential Internalization of Thrombin-Derived Host Defense Peptides into Monocytes and Macrophages

Proteolytic cleavage of thrombin generates C-terminal host defense peptides exerting multiple immunomodulatory effects in response to bacterial stimuli. Previously, we reported that thrombin-derived C-terminal peptides (TCPs) are internalized in monocytes and macrophages in a time- and temperature-d...

Full description

Bibliographic Details
Main Authors: Finja C. Hansen, Aftab Nadeem, Kathryn L. Browning, Mario Campana, Artur Schmidtchen, Mariena J.A. van der Plas
Format: Article
Language:English
Published: Karger Publishers 2021-12-01
Series:Journal of Innate Immunity
Subjects:
Online Access:https://www.karger.com/Article/FullText/520831