THE ROLE OF DNA-METHYLTRANSFERASES IN THE LIFE CYCLE OF HEPATITIS B VIRUS AND PATHOGENESIS OF CHRONIC HEPATITIS B
Chronic hepatitis B is caused by a persistent form of hepatitis B virus, covalently closed circular DNA (cccDNA). Stability of cccDNA is associated with intracellular localization of cccDNA and formation of minichromosome, regulated by epigenetic mechanisms. One of the key mechanisms in epigenetics...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Central Research Institute for Epidemiology
2018-02-01
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Series: | Вопросы вирусологии |
Subjects: | |
Online Access: | https://virusjour.crie.ru/jour/article/viewFile/180/90 |