THE ROLE OF DNA-METHYLTRANSFERASES IN THE LIFE CYCLE OF HEPATITIS B VIRUS AND PATHOGENESIS OF CHRONIC HEPATITIS B

Chronic hepatitis B is caused by a persistent form of hepatitis B virus, covalently closed circular DNA (cccDNA). Stability of cccDNA is associated with intracellular localization of cccDNA and formation of minichromosome, regulated by epigenetic mechanisms. One of the key mechanisms in epigenetics...

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Bibliographic Details
Main Authors: D. S. Kostyushev, A. P. Zueva, S. A. Brezgin, A. D. Lipatnikov, E. V. Volchkova, V. V. Maleyev, V. P. Chulanov
Format: Article
Language:English
Published: Central Research Institute for Epidemiology 2018-02-01
Series:Вопросы вирусологии
Subjects:
Online Access:https://virusjour.crie.ru/jour/article/viewFile/180/90