Genomic G-quadruplex folding triggers a cytokine-mediated inflammatory feedback loop to aggravate inflammatory diseases

Genomic G-quadruplex folding triggers a cytokine-mediated inflammatory feedback loop to aggravate inflammatory diseases

Summary: DNA G-quadruplex is a non-canonical secondary structure that could epigenetically regulate gene expression. To investigate the regulating role of G-quadruplex, we devised an integrating method to perform the algorithm profiling and genome-wide analysis for the dynamic change of genomic G-qu...

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Bibliographic Details
Main Authors: Xiaolin Wang, Shunlun Chen, Zhuoyang Zhao, Fan Chen, Yuming Huang, Xingyu Guo, Linchuan Lei, Wantao Wang, Yanxin Luo, Huichuan Yu, Jianru Wang
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:iScience
Subjects:
Biological sciences
immunology
molecular biology
molecular mechanism of gene regulation
orthopedics
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422201584X

Internet

http://www.sciencedirect.com/science/article/pii/S258900422201584X

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