Global proteomics insights for a novel small compound targeting the non-integrin Laminin Receptor in a macrophage cell model

Global proteomics insights for a novel small compound targeting the non-integrin Laminin Receptor in a macrophage cell model

Introduction: Monocytes and macrophages are the first barrier of the innate immune system, which interact with agents causing osteoarthritis or other conditions, leading to the release of proinflammatory mediators that exacerbate inflammation.Methods: The aim of this study was to investigate the pro...

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Bibliographic Details
Main Authors: Abigail Haffner, Manoel Figueiredo Neto, C. Samuel Umbaugh, Tiago J. P. Sobreira, Timothy B. Lescun, Herman O. Sintim, Marxa L. Figueiredo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Drug Discovery
Subjects:
small molecules
PEDF
non-integrin laminin receptor
RPSA
drug discovery
anti-inflammatory
Online Access:https://www.frontiersin.org/articles/10.3389/fddsv.2023.1326736/full

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https://www.frontiersin.org/articles/10.3389/fddsv.2023.1326736/full

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