Inhibition of CCR8 attenuates Ang Ⅱ-induced vascular smooth muscle cell injury by suppressing the MAPK/NF-κB pathway

Inhibition of CCR8 attenuates Ang Ⅱ-induced vascular smooth muscle cell injury by suppressing the MAPK/NF-κB pathway

Objective(s): Hyperinsulinemia, secondary to insulin resistance, may lead to vascular smooth muscle cell dysfunction. In the present research, we aimed to investigate the effect of Chemokine receptor 8 (CCR8) on angiotensin II (Ang II)-induced dysfunction of vascular smooth muscle cells (VSMCs) and...

Full description

Bibliographic Details
Main Authors: Lisi Liao, Di Song, Bobo Shi, Ming Chen, Linghu Wu, Jinfeng Xu, Fajin Dong
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2022-09-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
ccr8
hypertension
inflammation
insulin resistance
mapk/nf-κb signaling
oxidative
Online Access:https://ijbms.mums.ac.ir/article_20871_7c87bdf12e729be478c716a46f834ed1.pdf

Internet

https://ijbms.mums.ac.ir/article_20871_7c87bdf12e729be478c716a46f834ed1.pdf

Similar Items