Crystal structure of a subtilisin-like autotransporter passenger domain reveals insights into its cytotoxic function

Crystal structure of a subtilisin-like autotransporter passenger domain reveals insights into its cytotoxic function

Autotransporters are bacterial proteins that possess multiple activities associated with pathogenesis. Here the authors present the structure of the autotransporter subtilase Ssp from Serratia marcescens and show that its distinctive structural features are required for its cytotoxic function.

Bibliographic Details
Main Authors: Lilian Hor, Akila Pilapitiya, James A. McKenna, Santosh Panjikar, Marilyn A. Anderson, Mickaël Desvaux, Jason J. Paxman, Begoña Heras
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36719-2

Internet

https://doi.org/10.1038/s41467-023-36719-2

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