Ahr1 and Tup1 Contribute to the Transcriptional Control of Virulence-Associated Genes in <named-content content-type="genus-species">Candida albicans</named-content>

Ahr1 and Tup1 Contribute to the Transcriptional Control of Virulence-Associated Genes in <named-content content-type="genus-species">Candida albicans</named-content>

ABSTRACT The capacity of Candida albicans to reversibly change its morphology between yeast and filamentous stages is crucial for its virulence. Formation of hyphae correlates with the upregulation of genes ALS3 and ECE1, which are involved in pathogenicity processes such as invasion, iron acquisiti...

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Main Authors: Sophia Ruben, Enrico Garbe, Selene Mogavero, Daniela Albrecht-Eckardt, Daniela Hellwig, Antje Häder, Thomas Krüger, Katrin Gerth, Ilse D. Jacobsen, Osama Elshafee, Sascha Brunke, Kerstin Hünniger, Olaf Kniemeyer, Axel A. Brakhage, Joachim Morschhäuser, Bernhard Hube, Slavena Vylkova, Oliver Kurzai, Ronny Martin
Format: Article
Language:English
Published: American Society for Microbiology 2020-04-01
Series:mBio
Subjects:
Candida albicans
Tup1
filamentation
fungal virulence
gene regulation
Online Access:https://journals.asm.org/doi/10.1128/mBio.00206-20

Internet

https://journals.asm.org/doi/10.1128/mBio.00206-20

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