N-Terminal Regions of Prion Protein: Functions and Roles in Prion Diseases
The normal cellular isoform of prion protein, designated PrP<sup>C</sup>, is constitutively converted to the abnormally folded, amyloidogenic isoform, PrP<sup>Sc</sup>, in prion diseases, which include Creutzfeldt-Jakob disease in humans and scrapie and bovine spongiform ence...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-08-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/17/6233 |