Oral treatment with the all-d-peptide RD2 enhances cognition in aged beagle dogs – A model of sporadic Alzheimer’s disease

Oral treatment with the all-d-peptide RD2 enhances cognition in aged beagle dogs – A model of sporadic Alzheimer’s disease

Disease-modifying therapies to treat Alzheimer's disease (AD) are of fundamental interest for aging humans, societies, and health care systems. Predictable disease progression in transgenic AD models favors preclinical studies employing a preventive study design with an early pre-symptomatic tr...

Full description

Bibliographic Details
Main Authors: Janine Kutzsche, Sarah Schemmert, Tuyen Bujnicki, Christian Zafiu, Steffen Halbgebauer, Victoria Kraemer-Schulien, Marlene Pils, Lara Blömeke, Julia Post, Andreas Kulawik, Dagmar Jürgens, Wolfgang M. Rossberg, Michael Hümpel, Oliver Bannach, Markus Otto, Joseph A. Araujo, Antje Willuweit, Dieter Willbold
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Heliyon
Subjects:
Alzheimer's disease
Aβ oligomers
Tau oligomers
Cognitively impaired aged Beagle dogs
Sporadic AD animal model
Disease-modifying therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023056517

Internet

http://www.sciencedirect.com/science/article/pii/S2405844023056517

Similar Items