Development of a Fluorescent Quenching Based High Throughput Assay to Screen for Calcineurin Inhibitors.

Currently there is no effective treatment available for major neurodegenerative disorders associated to protein misfolding, including Alzheimer's and Parkinson's disease. One of most promising therapeutic approaches under development focuses on inhibiting the misfolding and aggregation pat...

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Bibliographic Details
Main Authors: Abhisek Mukherjee, Kathleen Syeb, John Concannon, Keri Callegari, Claudio Soto, Marcie A Glicksman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4503349?pdf=render