Chronic Sodium Selenate Treatment Restores Deficits in Cognition and Synaptic Plasticity in a Murine Model of Tauopathy

Chronic Sodium Selenate Treatment Restores Deficits in Cognition and Synaptic Plasticity in a Murine Model of Tauopathy

A major goal in diseases is identifying a potential therapeutic agent that is cost-effective and can remedy some, if not all, disease symptoms. In Alzheimer’s disease (AD), aggregation of hyperphosphorylated tau protein is one of the neuropathological hallmarks, and Tau pathology correlates better w...

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Bibliographic Details
Main Authors: Tariq Ahmed, Ann Van der Jeugd, Raphaëlle Caillierez, Luc Buée, David Blum, Rudi D’Hooge, Detlef Balschun
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Alzheimer’s disease
chronic oral treatment
synaptic transmission
synaptic plasticity
long-term depression
neurocognitive functions
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2020.570223/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2020.570223/full

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