Biomimetic hypoxia-triggered RNAi nanomedicine for synergistically mediating chemo/radiotherapy of glioblastoma

Biomimetic hypoxia-triggered RNAi nanomedicine for synergistically mediating chemo/radiotherapy of glioblastoma

Abstract Although RNA interference (RNAi) therapy has emerged as a potential tool in cancer therapeutics, the application of RNAi to glioblastoma (GBM) remains a hurdle. Herein, to improve the therapeutic effect of RNAi on GBM, a cancer cell membrane (CCM)-disguised hypoxia-triggered RNAi nanomedici...

Full description

Bibliographic Details
Main Authors: Zhen Wang, Xiang-long Tang, Meng-jie Zhao, Yi-ding Zhang, Yong Xiao, Yu-yang Liu, Chun-fa Qian, Yan-dong Xie, Yong Liu, Yuan-jie Zou, Kun Yang, Hong-yi Liu
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Journal of Nanobiotechnology
Subjects:
Cancer cell membrane
Hypoxia-triggered
Chemotherapy
Radiotherapy
siRNA delivery
Glioblastoma
Online Access:https://doi.org/10.1186/s12951-023-01960-w

Internet

https://doi.org/10.1186/s12951-023-01960-w

Similar Items