Perm1 regulates cardiac energetics as a downstream target of the histone methyltransferase Smyd1.

Perm1 regulates cardiac energetics as a downstream target of the histone methyltransferase Smyd1.

The transcriptional regulatory machinery in mitochondrial bioenergetics is complex and is still not completely understood. We previously demonstrated that the histone methyltransferase Smyd1 regulates mitochondrial energetics. Here, we identified Perm1 (PPARGC-1 and ESRR-induced regulator, muscle sp...

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Bibliographic Details
Main Authors: Shin-Ichi Oka, Amira D Sabry, Amanda K Horiuchi, Keiko M Cawley, Sean A O'Very, Maria A Zaitsev, Thirupura S Shankar, Jaemin Byun, Risa Mukai, Xiaoyong Xu, Natalia S Torres, Anil Kumar, Masayuki Yazawa, Jing Ling, Iosif Taleb, Yukio Saijoh, Stavros G Drakos, Junichi Sadoshima, Junco S Warren
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0234913

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https://doi.org/10.1371/journal.pone.0234913

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