Obese Male Mice Exposed to Early Life Stress Display Sympathetic Activation and Hypertension Independent of Circulating Angiotensin II

Obese Male Mice Exposed to Early Life Stress Display Sympathetic Activation and Hypertension Independent of Circulating Angiotensin II

Background We have previously reported that male mice exposed to maternal separation and early weaning (MSEW), a model of early life stress, show sympathetic activation and increased blood pressure in response to a chronic high‐fat diet. The goal of this study was to investigate the contribution of...

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Bibliographic Details
Main Authors: Carolina Dalmasso, Nermin S. Ahmed, Sundus Ghuneim, Cole Cincinelli, Jaqueline R. Leachman, Jorge F. Giani, Lisa Cassis, Analia S. Loria
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
adipose tissue
hypertension
maternal separation
obesity
renin–angiotensin system
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.123.029511

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.123.029511

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