SNP-ChIP: a versatile and tag-free method to quantify changes in protein binding across the genome

SNP-ChIP: a versatile and tag-free method to quantify changes in protein binding across the genome

Abstract Background Chromatin-immunoprecipitation followed by sequencing (ChIP-seq) is the method of choice for mapping genome-wide binding of chromatin-associated factors. However, broadly applicable methods for between-sample comparisons are lacking. Results Here, we introduce SNP-ChIP, a method t...

Full description

Bibliographic Details
Main Authors: Luis A. Vale-Silva, Tovah E. Markowitz, Andreas Hochwagen
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Genomics
Subjects:
Chromatin immunoprecipitation
ChIP-seq
Spike-in
Normalization
Chromosomal proteins
Post-translational modification
Online Access:http://link.springer.com/article/10.1186/s12864-018-5368-4

Internet

http://link.springer.com/article/10.1186/s12864-018-5368-4

Similar Items