Plasmodium Perforin-Like Protein Pores on the Host Cell Membrane Contribute in Its Multistage Growth and Erythrocyte Senescence

Plasmodium Perforin-Like Protein Pores on the Host Cell Membrane Contribute in Its Multistage Growth and Erythrocyte Senescence

The pore forming Plasmodium Perforin Like Proteins (PPLP), expressed in all stages of the parasite life cycle are critical for completion of the parasite life cycle. The high sequence similarity in the central Membrane Attack Complex/ Perforin (MACPF) domain among PLPs and their distinct functional...

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Bibliographic Details
Main Authors: Swati Garg, Abhishek Shivappagowdar, Rahul S. Hada, Rajagopal Ayana, Chandramohan Bathula, Subhabrata Sen, Inderjeet Kalia, Soumya Pati, Agam P. Singh, Shailja Singh
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
perforin like proteins
malaria
erythrocyte
anemia
invasion
egress
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00121/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2020.00121/full

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