Mice With Decreased Number of Interneurons Exhibit Aberrant Spontaneous and Oscillatory Activity in the Cortex

Mice With Decreased Number of Interneurons Exhibit Aberrant Spontaneous and Oscillatory Activity in the Cortex

GABAergic (γ-aminobutyric acid) neurons are inhibitory neurons and protect neural tissue from excessive excitation. Cortical GABAergic neurons play a pivotal role for the generation of synchronized cortical network oscillations. Imbalance between excitatory and inhibitory mechanisms underlies many n...

Full description

Bibliographic Details
Main Authors: Katerina Kalemaki, Xanthippi Konstantoudaki, Simona Tivodar, Kyriaki Sidiropoulou, Domna Karagogeos
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Neural Circuits
Subjects:
MGE-derived interneurons
Rac1
synaptic plasticity
neuronal oscillations
high K+ aCSF
Online Access:https://www.frontiersin.org/article/10.3389/fncir.2018.00096/full

Internet

https://www.frontiersin.org/article/10.3389/fncir.2018.00096/full

Similar Items