Trabecular bone organoids: a micron-scale ‘humanised’ prototype designed to study the effects of microgravity and degeneration

Abstract Bone is a highly responsive organ, which continuously adapts to the environment it is subjected to in order to withstand metabolic demands. These events are difficult to study in this particular tissue in vivo, due to its rigid, mineralised structure and inaccessibility of the cellular comp...

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Bibliographic Details
Main Authors: Alexandra Iordachescu, Erik A. B. Hughes, Stephan Joseph, Eric J. Hill, Liam M. Grover, Anthony D. Metcalfe
Format: Article
Language:English
Published: Nature Portfolio 2021-05-01
Series:npj Microgravity
Online Access:https://doi.org/10.1038/s41526-021-00146-8