Trabecular bone organoids: a micron-scale ‘humanised’ prototype designed to study the effects of microgravity and degeneration
Abstract Bone is a highly responsive organ, which continuously adapts to the environment it is subjected to in order to withstand metabolic demands. These events are difficult to study in this particular tissue in vivo, due to its rigid, mineralised structure and inaccessibility of the cellular comp...
Main Authors: | Alexandra Iordachescu, Erik A. B. Hughes, Stephan Joseph, Eric J. Hill, Liam M. Grover, Anthony D. Metcalfe |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-05-01
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Series: | npj Microgravity |
Online Access: | https://doi.org/10.1038/s41526-021-00146-8 |
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