Triptolide as a novel agent in pancreatic cancer: the validation using patient derived pancreatic tumor cell line

Triptolide as a novel agent in pancreatic cancer: the validation using patient derived pancreatic tumor cell line

Abstract Background Triptolide induces apoptosis and DNA damage followed by inhibition of DNA repair associated gene expression. However, there is the limited data for biomarker to predict the benefit to triptolide in various cancers including pancreatic cancer. Methods We investigated the anti tumo...

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Bibliographic Details
Main Authors: Seung Tae Kim, Sun Young Kim, Jeeyun Lee, Kyung Kim, Se Hoon Park, Young Suk Park, Ho Yeong Lim, Won Ki Kang, Joon Oh Park
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Cancer
Subjects:
Patient derived cells (PDCs)
Triptolide
Chk2
Online Access:http://link.springer.com/article/10.1186/s12885-018-4995-0

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http://link.springer.com/article/10.1186/s12885-018-4995-0

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