CNTN-1 Upregulation Induced by Low-Dose Cisplatin Promotes Malignant Progression of Lung Adenocarcinoma Cells via Activation of Epithelial-Mesenchymal Transition

CNTN-1 Upregulation Induced by Low-Dose Cisplatin Promotes Malignant Progression of Lung Adenocarcinoma Cells via Activation of Epithelial-Mesenchymal Transition

Tumor metastasis and invasion are the main impediments to lung adenocarcinoma successful treatment. Previous studies demonstrate that chemotherapeutic agents can elevate the malignancy of cancer cells other than their therapeutic effects. In this study, the effects of transient low-dose cisplatin tr...

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Bibliographic Details
Main Authors: Ruijie Zhang, Shengjin Li, Jian Lan, Changyi Li, Xianzhi Du, Weijie Dong, Qian Yu, Daoxin Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Genetics
Subjects:
CNTN-1
EMT
cisplatin
A549 cell
metastasis
invasion
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.891665/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.891665/full

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