The modulatory effects of gut microbes and metabolites on blood–brain barrier integrity and brain function in sepsis-associated encephalopathy

Background Intestinal microbiota homeostasis and the gut-brain axis are key players associated with host health and alterations in metabolic, inflammatory, and neurodegenerative disorders. Sepsis-associated encephalopathy (SAE), which is closely associated with bacterial translocation, is a common s...

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Bibliographic Details
Main Authors: Zhaoying Li, Fangxiang Zhang, Meisha Sun, Jia Liu, Li Zhao, Shuchun Liu, Shanshan Li, Bin Wang
Format: Article
Language:English
Published: PeerJ Inc. 2023-03-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/15122.pdf