p38 MAPK activity is associated with the histological degree of interstitial fibrosis in IgA nephropathy patients.

Activation of p38 mitogen-activated protein kinase (MAPK) is associated with tissue fibrosis, and inhibition of p38 MAPK can attenuate the progression of fibrosis. We aimed to investigate whether p38 MAPK activity in kidney tissue confirmed by immunohistochemical staining is associated with renal tu...

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Bibliographic Details
Main Authors: Jeonghwan Lee, Jung Nam An, Jin Ho Hwang, Hajeong Lee, Jung Pyo Lee, Sung Gyun Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0213981