Ubiquitin Engineering for Interrogating the Ubiquitin–Proteasome System and Novel Therapeutic Strategies

Protein turnover, a highly regulated process governed by the ubiquitin–proteasome system (UPS), is essential for maintaining cellular homeostasis. Dysregulation of the UPS has been implicated in various diseases, including viral infections and cancer, making the proteins in the UPS attractive target...

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Bibliographic Details
Main Authors: Jason Q. Tang, Mary M. Marchand, Gianluca Veggiani
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/16/2117