Cellular Phenotypic Transformation in Heart Failure Caused by Coronary Heart Disease and Dilated Cardiomyopathy: Delineating at Single-Cell Level

Cellular Phenotypic Transformation in Heart Failure Caused by Coronary Heart Disease and Dilated Cardiomyopathy: Delineating at Single-Cell Level

Heart failure (HF) is known as the final manifestation of cardiovascular diseases. Although cellular heterogeneity of the heart is well understood, the phenotypic transformation of cardiac cells in progress of HF remains obscure. This study aimed to analyze phenotypic transformation of cardiac cells...

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Bibliographic Details
Main Authors: Luojiang Zhu, Wen Wang, Changzhen Ren, Yangkai Wang, Guanghao Zhang, Jianmin Liu, Weizhong Wang
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biomedicines
Subjects:
heart failure
coronary heart disease
single-cell RNA sequencing
phenotypic transformation
myosin
cardiac fibrosis
Online Access:https://www.mdpi.com/2227-9059/10/2/402

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https://www.mdpi.com/2227-9059/10/2/402

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