Programmed expression of pro-apoptotic BMCC1 during apoptosis, triggered by DNA damage in neuroblastoma cells

Programmed expression of pro-apoptotic BMCC1 during apoptosis, triggered by DNA damage in neuroblastoma cells

Abstract Background The multi-functional BMCC1 (BCH motif-containing molecule at the carboxyl terminal region 1)/PRUNE2 plays a clear role in suppression of tumor activity. In the patients with neuroblastoma (NB), reduced expression of BMCC1 in primary tumor tissues was associated with poor prognosi...

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Bibliographic Details
Main Authors: Mohammad Sazzadul Islam, Ryo Takano, Tomoki Yokochi, Jesmin Akter, Yohko Nakamura, Akira Nakagawara, Yasutoshi Tatsumi
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Cancer
Subjects:
BMCC1
E2F1
Apoptosis
Caspase-9
DNA damage
Neuroblastoma
Online Access:http://link.springer.com/article/10.1186/s12885-019-5772-4

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http://link.springer.com/article/10.1186/s12885-019-5772-4

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