Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes

Fusion of multivesicular bodies (MVBs) with the plasma membrane results in the secretion of intraluminal vesicles (ILVs), or exosomes. The sorting of one exosomal cargo RNA, miR223, is facilitated by the RNA-binding protein, YBX1 (Shurtleff et al., 2016). We found that miR223 specifically binds a ‘c...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Liang Ma, Jasleen Singh, Randy Schekman
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: eLife Sciences Publications Ltd 2023-07-01
Sraith:eLife
Ábhair:
Rochtain ar líne:https://elifesciences.org/articles/85878