Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes
Fusion of multivesicular bodies (MVBs) with the plasma membrane results in the secretion of intraluminal vesicles (ILVs), or exosomes. The sorting of one exosomal cargo RNA, miR223, is facilitated by the RNA-binding protein, YBX1 (Shurtleff et al., 2016). We found that miR223 specifically binds a ‘c...
| Những tác giả chính: | , , |
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| Định dạng: | Bài viết |
| Ngôn ngữ: | English |
| Được phát hành: |
eLife Sciences Publications Ltd
2023-07-01
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| Loạt: | eLife |
| Những chủ đề: | |
| Truy cập trực tuyến: | https://elifesciences.org/articles/85878 |