De Novo Design and Synthesis of Polypeptide Immunomodulators for Resetting Macrophage Polarization

De Novo Design and Synthesis of Polypeptide Immunomodulators for Resetting Macrophage Polarization

Modulating the extracellular matrix microenvironment is critical for achieving the desired macrophage phenotype in immune investigations or tumor therapy. Combining de novo protein design and biosynthesis techniques, herein, we designed a biomimetic polypeptide self-assembled nano-immunomodulator to...

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Bibliographic Details
Main Authors: Na Kong, Hongru Ma, Zhongji Pu, Fengju Wan, Dongfang Li, Lei Huang, Jiazhang Lian, Xingxu Huang, Shengjie Ling, Haoran Yu, Yuan Yao
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2023-01-01
Series:BioDesign Research
Online Access:https://spj.science.org/doi/10.34133/bdr.0006

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https://spj.science.org/doi/10.34133/bdr.0006

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