Chaperonin CCT controls extracellular vesicle production and cell metabolism through kinesin dynamics

Chaperonin CCT controls extracellular vesicle production and cell metabolism through kinesin dynamics

Abstract Cell proteostasis includes gene transcription, protein translation, folding of de novo proteins, post‐translational modifications, secretion, degradation and recycling. By profiling the proteome of extracellular vesicles (EVs) from T cells, we have found the chaperonin complex CCT, involved...

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Bibliographic Details
Main Authors: Amelia Rojas‐Gómez, Sara G. Dosil, Francisco J. Chichón, Nieves Fernández‐Gallego, Alessia Ferrarini, Enrique Calvo, Diego Calzada‐Fraile, Silvia Requena, Joaquin Otón, Alvaro Serrano, Rocio Tarifa, Montserrat Arroyo, Andrea Sorrentino, Eva Pereiro, Jesus Vázquez, José M. Valpuesta, Francisco Sánchez‐Madrid, Noa B. Martín‐Cófreces
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Journal of Extracellular Vesicles
Subjects:
CCT
chaperonin
extracellular vesicle
lipid droplet
lipidomic
peroxisome
Online Access:https://doi.org/10.1002/jev2.12333

Internet

https://doi.org/10.1002/jev2.12333

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