Development of a Novel PET Tracer [18F]AlF-NOTA-C6 Targeting MMP2 for Tumor Imaging.

Development of a Novel PET Tracer [18F]AlF-NOTA-C6 Targeting MMP2 for Tumor Imaging.

The overexpression of gelatinases, that is, matrix metalloproteinase MMP2 and MMP9, has been associated with tumor progression, invasion, and metastasis. To image MMP2 in tumors, we developed a novel ligand termed [18F]AlF-NOTA-C6, with consideration that: c(KAHWGFTLD)NH2 (herein, C6) is a selective...

Полное описание

Библиографические подробности
Главные авторы: Qinghua Liu, Donghui Pan, Chao Cheng, Dazhi Zhang, Anyu Zhang, Lizhen Wang, Hongdie Jiang, Tao Wang, Hongrui Liu, Yuping Xu, Runlin Yang, Fei Chen, Min Yang, Changjing Zuo
Формат: Статья
Язык:English
Опубликовано: Public Library of Science (PLoS) 2015-01-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC4634933?pdf=render

Internet

http://europepmc.org/articles/PMC4634933?pdf=render

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