The Inflammatory Profile of CTEPH-Derived Endothelial Cells Is a Possible Driver of Disease Progression

The Inflammatory Profile of CTEPH-Derived Endothelial Cells Is a Possible Driver of Disease Progression

Chronic thromboembolic pulmonary hypertension (CTEPH) is a form of pulmonary hypertension characterized by the presence of fibrotic intraluminal thrombi and causing obliteration of the pulmonary arteries. Although both endothelial cell (EC) dysfunction and inflammation are linked to CTEPH pathogenes...

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Bibliographic Details
Main Authors: Valérie F. E. D. Smolders, Kirsten Lodder, Cristina Rodríguez, Olga Tura-Ceide, Joan Albert Barberà, J. Wouter Jukema, Paul H. A. Quax, Marie José Goumans, Kondababu Kurakula
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
chronic thromboembolic pulmonary hypertension
inflammation
nuclear factor-κB signaling
endothelial dysfunction
Online Access:https://www.mdpi.com/2073-4409/10/4/737

Internet

https://www.mdpi.com/2073-4409/10/4/737

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