Lnc-DC promotes estrogen independent growth and tamoxifen resistance in breast cancer

Abstract Selective estrogen receptor modulators (SERMs) such as tamoxifen have proven to be effective in the treatment of estrogen receptor (ER) positive breast cancer. However, a major obstacle for such endocrine therapy is estrogen independent growth, leading to resistance, and the underlying mech...

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Bibliographic Details
Main Authors: Wan-Xin Peng, Pratirodh Koirala, Huaixiang Zhou, Jiahong Jiang, Ziqiang Zhang, Liu Yang, Yin-Yuan Mo
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-04288-1