The neuroprotective effect of nicotine in Parkinson’s disease models is associated with inhibiting PARP-1 and caspase-3 cleavage
Clinical evidence points to neuroprotective effects of smoking in Parkinson’s disease (PD), but the molecular mechanisms remain unclear. We investigated the pharmacological pathways involved in these neuroprotective effects, which could provide novel ideas for developing targeted neuroprotective tre...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2017-10-01
|
Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/3933.pdf |