A Pyrazolate Osmium(VI) Nitride Exhibits Anticancer Activity through Modulating Protein Homeostasis in HepG2 Cells

A Pyrazolate Osmium(VI) Nitride Exhibits Anticancer Activity through Modulating Protein Homeostasis in HepG2 Cells

Interest in the third-row transition metal osmium and its compounds as potential anticancer agents has grown in recent years. Here, we synthesized the osmium(VI) nitrido complex <b>Na[Os<sup>VI</sup>(N)(tpm)<sub>2</sub>]</b> (tpm = [5-(Thien-2-yl)-1H-pyrazol-3-yl]...

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Bibliographic Details
Main Authors: Chengyang Huang, Wanqiong Huang, Pengchao Ji, Fuling Song, Tao Liu, Meiyang Li, Hongzhi Guo, Yongliang Huang, Cuicui Yu, Chuanxian Wang, Wenxiu Ni
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
osmium complex
pyrazole derivatives
anticancer
protein homeostasis
apoptosis
Online Access:https://www.mdpi.com/1422-0067/23/21/12779

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https://www.mdpi.com/1422-0067/23/21/12779

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